No pain can be greater than the pain of one person. [...] In other words, no suffering can be greater than that of one human being. [...} The whole planet cannot suffer more than a lone soul.
No one wants to die. Even people who want to go to heaven don’t want to die to get there. And yet death is the destination we all share. No one has ever escaped it. And that is as it should be, because Death is very likely the single best invention of Life. It is Life’s change agent. It clears out the old to make way for the new. Right now the new is you, but someday not too long from now, you will gradually become the old and be cleared away. Sorry to be so dramatic, but it is quite true.
The thinkers of the Enlightenment sought a new understanding of the human condition. The era was a cornucopia of ideas, some of them contradictory, but four themes tie them together: reason, science, humanism, and progress.
I was once interviewed in Italy and the headline of the interview the next day was wonderful. I saved this for my collection it was... "YES we have a soul but it's made of lots of tiny robots" and I thought that's exactly right. Yes we have a soul, but it's mechanical. But it's still a soul, it still does the work that the soul was supposed to do. It is the seat of reason. It is the seat of moral responsibility. It's why we are appropriate objects of punishment when we do evil things, why we deserve the praise when we do good things. It's just not a mysterious lump of wonder stuff... that will out live us.
Because it is the last to mature, by definition the frontal cortex is the brain region least constrained by genes and most sculpted by experience. This must be so, to be the supremely complex social species that we are. Ironically, it seems that the genetic program of human brain development has evolved to, as much as possible, free the frontal cortex from genes.